Gene

ripk2

ID
ZDB-GENE-030902-3
Name
receptor-interacting serine-threonine kinase 2
Symbol
ripk2 Nomenclature History
Previous Names
  • RICK (1)
  • Ripk2 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have CARD domain binding activity and protein serine/threonine kinase activity. Involved in defense response to other organism and regulation of transcription, DNA-templated. Predicted to localize to cytosol and mitochondrion. Is expressed in brain; gill; liver; pleuroperitoneal region; and unfertilized egg. Orthologous to human RIPK2 (receptor interacting serine/threonine kinase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ripk2 Human Ortholog
No data available
Associated With ripk2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Domain IPR000719 Protein kinase domain
Domain IPR001315 CARD domain
Domain IPR042149 RIP2, CARD domain
Family IPR017322 Receptor-interacting serine/threonine-protein kinase 2
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR011029 Death-like domain superfamily
Domain Details Per Protein
Protein Length CARD domain Death-like domain superfamily Protein kinase domain Protein kinase-like domain superfamily Receptor-interacting serine/threonine-protein kinase 2 RIP2, CARD domain Serine/threonine-protein kinase, active site
UniProtKB:A0A0R4IKJ5 457
UniProtKB:A5A8K0 418
UniProtKB:Q4V958 584
UniProtKB:Q8JHU4 584
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations