Gene

pcnt

ID
ZDB-GENE-030829-26
Name
pericentrin
Symbol
pcnt Nomenclature History
Previous Names
  • fc85c01
  • sb:cb754 (1)
  • si:ch211-245b3.1
  • wu:fc85c01
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have DNA binding activity and molecular adaptor activity. Predicted to be involved in signal transduction. Predicted to localize to cytoplasm and microtubule organizing center. Is expressed in several structures, including digestive system; heart tube; nervous system; pectoral fin musculature; and pronephric duct. Human ortholog(s) of this gene implicated in microcephalic osteodysplastic primordial dwarfism type II. Orthologous to human PCNT (pericentrin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Sepulveda et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pcnt Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
microcephalic osteodysplastic primordial dwarfism type II Alliance Microcephalic osteodysplastic primordial dwarfism, type II 210720
Associated With pcnt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005539 ELK domain
Domain IPR019528 Pericentrin/AKAP-450 centrosomal targeting domain
Family IPR028745 A-kinase anchor protein 9/Pericentrin
Domain Details Per Protein
Protein Length A-kinase anchor protein 9/Pericentrin ELK domain Pericentrin/AKAP-450 centrosomal targeting domain
UniProtKB:I3ISP1 4245
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations