Gene

e2f5

ID
ZDB-GENE-030828-3
Name
E2F transcription factor 5
Symbol
e2f5 Nomenclature History
Previous Names
  • cb735 (1)
  • zgc:111879
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to RNA polymerase II transcription regulator complex. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; liver; nervous system; and pleuroperitoneal region. Orthologous to human E2F5 (E2F transcription factor 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With e2f5 Human Ortholog
No data available
Associated With e2f5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003316 E2F/DP family, winged-helix DNA-binding domain
Domain IPR032198 E2F transcription factor, CC-MB domain
Family IPR015633 E2F Family
Family IPR028316 Transcription factor E2F5
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Homologous_superfamily IPR037241 E2F-DP heterodimerization region
Domain Details Per Protein
Protein Length E2F/DP family, winged-helix DNA-binding domain E2F-DP heterodimerization region E2F Family E2F transcription factor, CC-MB domain Transcription factor E2F5 Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:Q6TH18 143
UniProtKB:A5WUE8 363
UniProtKB:Q4KMF0 363
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations