Gene
tjp3
- ID
- ZDB-GENE-030828-10
- Name
- tight junction protein 3
- Symbol
- tjp3 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable cell adhesion molecule binding activity. Acts upstream of or within multicellular organismal homeostasis and water homeostasis. Located in bicellular tight junction. Is expressed in several structures, including digestive system; integument; mesoderm; pleuroperitoneal region; and sensory system. Orthologous to human TJP3 (tight junction protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb766 (23 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Kiener et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR008144 | Guanylate kinase-like domain |
| Domain | IPR008145 | Guanylate kinase/L-type calcium channel beta subunit |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | Guanylate kinase-like domain | Guanylate kinase/L-type calcium channel beta subunit | PDZ domain | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BHQ8
|
1255 |
Interactions and Pathways
No data available
Plasmids
No data available