Gene

casp8ap2

ID
ZDB-GENE-030826-8
Name
caspase 8 associated protein 2
Symbol
casp8ap2 Nomenclature History
Previous Names
  • fc74h10
  • FLASH
  • wu:fc74h10
  • zgc:113449
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable transcription corepressor activity. Predicted to be involved in Fas signaling pathway; activation of cysteine-type endopeptidase activity involved in apoptotic process; and extrinsic apoptotic signaling pathway via death domain receptors. Predicted to act upstream of or within apoptotic signaling pathway. Predicted to be active in PML body and mitochondrion. Orthologous to human CASP8AP2 (caspase 8 associated protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With casp8ap2 Human Ortholog
No data available
Associated With casp8ap2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR039674 CASP8-associated protein 2
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length CASP8-associated protein 2 Homeobox-like domain superfamily
UniProtKB:Q58EM6 274
UniProtKB:F1QD18 1995
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations