Gene

mvp

ID
ZDB-GENE-030826-33
Name
major vault protein
Symbol
mvp Nomenclature History
Previous Names
  • cb771 (1)
  • wu:fb52b05
  • wu:fc02g01
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Involved in brain development; eye development; and neuron projection regeneration. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including digestive system; hatching gland; nervous system; periderm; and polster. Human ortholog(s) of this gene implicated in mitral valve prolapse. Orthologous to human MVP (major vault protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Blaker-Lee et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mvp Human Ortholog
No data available
Associated With mvp Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR021870 Major vault protein, shoulder domain
Domain IPR040989 Major vault protein repeat domain 3
Domain IPR041134 Major vault protein repeat domain 2
Domain IPR041136 Major vault protein repeat domain 4
Domain IPR041139 Major vault protein repeat domain
Family IPR039059 Major vault protein
Homologous_superfamily IPR043023 Major vault protein repeat domain superfamily
Homologous_superfamily IPR043179 Major vault protein repeat domain 2 superfamily
Repeat IPR002499 Major vault protein, N-terminal
Domain Details Per Protein
Protein Length IQ motif, EF-hand binding site Major vault protein Major vault protein, N-terminal Major vault protein repeat domain Major vault protein repeat domain 2 Major vault protein repeat domain 2 superfamily Major vault protein repeat domain 3 Major vault protein repeat domain 4 Major vault protein repeat domain superfamily Major vault protein, shoulder domain
UniProtKB:F1Q781 869
UniProtKB:Q6P3L0 863
UniProtKB:E9QEQ6 870
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations