ZFIN is now using GRCz12tu for Genomic Data
Gene
hif1an
- ID
- ZDB-GENE-030826-19
- Name
- hypoxia inducible factor 1 subunit alpha inhibitor
- Symbol
- hif1an Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including 2-oxoglutarate-dependent dioxygenase activity; protein homodimerization activity; and transition metal ion binding activity. Acts upstream of or within negative regulation of vasculature development and regulation of vascular endothelial growth factor receptor signaling pathway. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alar plate midbrain region; central nervous system; immature eye; midbrain hindbrain boundary neural rod; and midbrain neural keel. Orthologous to human HIF1AN (hypoxia inducible factor 1 subunit alpha inhibitor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb728 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cupin-like domain 8 | Hypoxia-inducible factor 1-alpha inhibitor, domain II | JmjC domain | RmlC-like jelly roll fold |
|---|---|---|---|---|---|---|
| UniProtKB:P59723 | InterPro | 344 | ||||
| UniProtKB:B2GNZ2 | InterPro | 344 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hif1an-201
(1)
|
Ensembl | 2,160 nt | ||
| ncRNA |
hif1an-002
(1)
|
Ensembl | 520 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers