Gene
mcl1b
- ID
- ZDB-GENE-030825-1
- Name
- MCL1 apoptosis regulator, BCL2 family member b
- Symbol
- mcl1b Nomenclature History
- Previous Names
-
- zgc:109763
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Exhibits protein heterodimerization activity. Involved in chordate embryonic development; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; and negative regulation of mitotic nuclear division. Predicted to localize to mitochondrial outer membrane. Is expressed in brain; digestive system; eye; heart; and pleuroperitoneal region. Orthologous to human MCL1 (MCL1 apoptosis regulator, BCL2 family member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109763 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Apoptosis regulator, Mcl-1 | Bcl-2, Bcl-2 homology region 1-3 | Bcl-2 family | Bcl2-like | Bcl-2-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q568W5
|
228 |
Interactions and Pathways
No data available
Plasmids
No data available