Gene
mcl1b
- ID
- ZDB-GENE-030825-1
- Name
- MCL1 apoptosis regulator, BCL2 family member b
- Symbol
- mcl1b Nomenclature History
- Previous Names
-
- zgc:109763
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable channel activity. Acts upstream of or within chordate embryonic development and negative regulation of apoptotic process. Predicted to be located in nucleus. Predicted to be active in mitochondrial outer membrane. Is expressed in brain; digestive system; eye; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; lung cancer; and lung non-small cell carcinoma. Orthologous to human MCL1 (MCL1 apoptosis regulator, BCL2 family member).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109763 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Apoptosis regulator, Mcl-1 | Bcl-2, Bcl-2 homology region 1-3 | Bcl-2 family | Bcl2-like | Bcl-2-like superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q568W5
|
228 |
Interactions and Pathways
No data available
Plasmids
No data available