Gene
sult1st3
- ID
- ZDB-GENE-030804-28
- Name
- sulfotransferase family 1, cytosolic sulfotransferase 3
- Symbol
- sult1st3 Nomenclature History
- Previous Names
-
- wu:fj78b11
- zgc:92322
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Enables sulfotransferase activity. Involved in xenobiotic metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in breast cancer and endometrial cancer. Orthologous to human SULT1E1 (sulfotransferase family 1E member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa697 | Allele with one point mutation | Unknown | Premature Stop | ENU |
1 - 1 of 1
Show
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|
| UniProtKB:Q7T2V2 | InterPro | 301 | ||
| UniProtKB:Q6DHG7 | InterPro | 301 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
sult1st3-201
(1)
|
Ensembl | 1,625 nt | ||
| mRNA |
sult1st3-202
(1)
|
Ensembl | 1,474 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-196G2 | ZFIN Curated Data | |
| Encodes | EST | fj78b11 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:92322 | ZFIN Curated Data |
1 - 3 of 3
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_183348 (1) | 1501 nt | ||
| Genomic | GenBank:AL935148 (2) | 195396 nt | ||
| Polypeptide | UniProtKB:Q6DHG7 (1) | 301 aa |
No data available
- Adam, A.C., Lie, K.K., Whatmore, P., Jakt, L.M., Moren, M., Skjærven, K.H. (2019) Profiling DNA methylation patterns of zebrafish liver associated with parental high dietary arachidonic acid. PLoS One. 14:e0220934
- Yamauchi, K., Katsumata, S., Ozaki, M. (2019) A prototype of the mammalian sulfotransferase 1 (SULT1) family in Xenopus laevis: molecular and enzymatic properties of XlSULT1B.S. Genes & genetic systems. 94(5):207-217
- Yang, J., Zhao, H., Chan, K.M. (2017) Toxic effects of polybrominated diphenyl ethers (BDE 47 and 99) and localization of BDE-99-induced cyp1a mRNA in zebrafish larvae.. Toxicology reports. 4:614-624
- Zhou, Z., Yang, J., Chan, K.M. (2017) Toxic effects of triclosan on a zebrafish (Danio rerio) liver cell line, ZFL. Aquatic toxicology (Amsterdam, Netherlands). 191:175-188
- Xi, Y., Seyoum, H., Liu, M.C. (2016) Role of SULT-mediated sulfation in the biotransformation of 2-butoxyethanol and sorbitan monolaurate: A study using zebrafish SULTs. Aquatic toxicology (Amsterdam, Netherlands). 177:19-21
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Yang, J., Chan, K.M. (2015) Evaluation of the toxic effects of brominated compounds (BDE-47, 99, 209, TBBPA) and bisphenol A (BPA) using a zebrafish liver cell line, ZFL. Aquatic toxicology (Amsterdam, Netherlands). 159C:138-147
- Hao, R., Bondesson, M., Singh, A.V., Riu, A., McCollum, C.W., Knudsen, T.B., Gorelick, D.A., and Gustafsson, J.Å. (2013) Identification of Estrogen Target Genes during Zebrafish Embryonic Development through Transcriptomic Analysis. PLoS One. 8(11):e79020
- Mohammed, Y.I., Kurogi, K., Shaban, A.A., Xu, Z., Liu, M.Y., Williams, F.E., Sakakibara, Y., Suiko, M., Bhuiyan, S., and Liu, M.C. (2012) Identification and characterization of zebrafish SULT1 ST9, SULT3 ST4, and SULT3 ST5. Aquatic toxicology (Amsterdam, Netherlands). 112-113C:11-18
- Kurogi, K., Dillon, J., Nasser, A., Liu, M.Y., Williams, F.E., Sakakibara, Y., Suiko, M., and Liu, M.C. (2010) Sulfation of Drug Compounds by the Zebrafish Cytosolic Sulfotransferases (SULTs). Drug metabolism letters. 4(2):62-68
1 - 10 of 13
Show