Gene

lamp2

ID
ZDB-GENE-030729-9
Name
lysosomal-associated membrane protein 2
Symbol
lamp2 Nomenclature History
Previous Names
  • sb:cb587
  • wu:fb14a06
  • zgc:103532
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Involved in macroautophagy. Predicted to localize to bounding membrane of organelle and plasma membrane. Is expressed in cardiovascular system; heart; solid lens vesicle; vein; and yolk syncytial layer. Used to study Danon disease. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Orthologous to human LAMP2 (lysosomal associated membrane protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Dvornikov et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lamp2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Danon disease 300257
Associated With lamp2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR048524 Lysosome-associated membrane glycoprotein 2-like, transmembrane domain
Domain IPR048528 Lysosome-associated membrane glycoprotein 2-like, luminal domains
Family IPR002000 Lysosome-associated membrane glycoprotein
Domain Details Per Protein
Protein Length Lysosome-associated membrane glycoprotein Lysosome-associated membrane glycoprotein 2-like, luminal domains Lysosome-associated membrane glycoprotein 2-like, transmembrane domain
UniProtKB:Q5BKX3 355
UniProtKB:A0A2R8Q0I4 358
UniProtKB:A0A0R4IZ00 356
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations