Gene
ppp1cb
- ID
- ZDB-GENE-030616-609
- Name
- protein phosphatase 1, catalytic subunit, beta isozyme
- Symbol
- ppp1cb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Exhibits protein heterodimerization activity. Involved in convergent extension involved in axis elongation and liver development. Predicted to localize to cytoplasm and nucleus. Is expressed in intestine and liver. Orthologous to human PPP1CB (protein phosphatase 1 catalytic subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Noonan syndrome-like disorder with loose anagen hair 2 | Alliance | Noonan syndrome-like disorder with loose anagen hair 2 | 617506 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004843 | Calcineurin-like phosphoesterase domain, ApaH type |
| Domain | IPR006186 | Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase |
| Domain | IPR031675 | Serine-threonine protein phosphatase, N-terminal |
| Family | IPR050341 | Serine/threonine-protein phosphatase PP1 catalytic subunit |
| Homologous_superfamily | IPR029052 | Metallo-dependent phosphatase-like |
Domain Details Per Protein
| Protein | Length | Calcineurin-like phosphoesterase domain, ApaH type | Metallo-dependent phosphatase-like | Serine-threonine protein phosphatase, N-terminal | Serine/threonine-protein phosphatase PP1 catalytic subunit | Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase |
|---|---|---|---|---|---|---|
|
UniProtKB:Q1JPZ8
|
327 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp1cb-201
(1)
|
Ensembl | 2,225 nt | ||
| ncRNA |
ppp1cb-002
(1)
|
Ensembl | 629 nt |
Interactions and Pathways
No data available
Plasmids
No data available