Gene
thoc2
- ID
- ZDB-GENE-030616-54
- Name
- THO complex 2
- Symbol
- thoc2 Nomenclature History
- Previous Names
-
- Tho2 (1)
- fb73e08
- fd21d11
- si:bz1o18.2
- wu:fb73e08
- wu:fd21d11
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to localize to THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human THOC2 (THO complex 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| X-linked intellectual disability-short stature-overweight syndrome | Alliance | Intellectual developmental disorder, X-linked syndromic, Kumar type | 300957 |
| Arthrogryposis multiplex congenita 7, X-linked | 301127 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | THO complex subunit 2 | THO complex subunit 2, N-terminal domain | THO complex, subunitTHOC2, C-terminal | THO complex, subunitTHOC2, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:F1R5B5
|
1535 | ||||
|
UniProtKB:F1QXF4
|
1560 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
thoc2-202
(1)
|
Ensembl | 5,492 nt | ||
| mRNA |
thoc2-203
(1)
|
Ensembl | 5,457 nt | ||
| mRNA |
thoc2-204
(1)
|
Ensembl | 1,063 nt | ||
| ncRNA |
thoc2-001
(1)
|
Ensembl | 5,471 nt | ||
| ncRNA |
thoc2-002
(1)
|
Ensembl | 352 nt | ||
| ncRNA |
thoc2-005
(1)
|
Ensembl | 2,584 nt | ||
| ncRNA |
thoc2-006
(1)
|
Ensembl | 574 nt |
Interactions and Pathways
No data available
Plasmids
No data available