Gene
abcc4
- ID
- ZDB-GENE-030616-511
- Name
- ATP binding cassette subfamily C member 4 (PEL blood group)
- Symbol
- abcc4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Exhibits efflux transmembrane transporter activity. Involved in detoxification and regulation of cilium assembly. Localizes to plasma membrane. Is expressed in several structures, including Kupffer's vesicle; digestive system; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1019 (12 images)
- eu668 (1 image)
- eu872 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017871 | ABC transporter-like, conserved site |
| Domain | IPR003439 | ABC transporter-like, ATP-binding domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR011527 | ABC transporter type 1, transmembrane domain |
| Domain | IPR030240 | ATP-binding cassette sub-family C member 4, six-transmembrane helical domain 1 |
| Domain | IPR047083 | ATP-binding cassette sub-family C member 4, six-transmembrane helical domain 2 |
| Family | IPR009147 | Cystic fibrosis transmembrane conductance regulator |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | ABC transporter-like, ATP-binding domain | ABC transporter-like, conserved site | ABC transporter type 1, transmembrane domain | ABC transporter type 1, transmembrane domain superfamily | ATP-binding cassette sub-family C member 4, six-transmembrane helical domain 1 | ATP-binding cassette sub-family C member 4, six-transmembrane helical domain 2 | Cystic fibrosis transmembrane conductance regulator | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q8QFL6
|
1327 |
Interactions and Pathways
No data available
Plasmids
No data available