Gene

wdr75

ID

ZDB-GENE-030616-5

Name

WD repeat domain 75

Symbol

wdr75 Nomenclature History

Previous Names

AK022581-like (1)
cb990 (1)
flj12519 (1)
si:by113d7.2
si:by134g18.1
si:by68f21.1
SI:dZ46I22.2
si:dz73o4.1
si:xx-113d7.2
wu:fb53f09
wu:fb96h05

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable RNA binding activity. Predicted to be involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Predicted to act upstream of or within rRNA processing. Predicted to be located in nucleus. Predicted to be active in nucleolus. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; nervous system; and segmental plate. Orthologous to human WDR75 (WD repeat domain 75).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb990 (13 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wdr75 Human Ortholog

No data available

Associated With wdr75 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR053826	WD repeat-containing protein 75
Homologous_superfamily	IPR011047	Quinoprotein alcohol dehydrogenase-like superfamily
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Quinoprotein alcohol dehydrogenase-like superfamily	WD40 repeat	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily	WD repeat-containing protein 75
UniProtKB:Q7ZVR1 InterPro	832

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ottdart00000003996 (1)	Havana	1,381 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	ottdart00000004047 (1)	Havana	2,729 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	wdr75-201 (1) Ensembl	Ensembl	2,784 nt	Select Tool ZFIN BLAST
ncRNA	wdr75-002 (1) Ensembl	Ensembl	678 nt	Select Tool ZFIN BLAST
ncRNA	wdr75-003 (1) Ensembl	Ensembl	837 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations