header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030616-47
Gene Name: phosphatase and tensin homolog B
Gene Symbol: ptenb
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: pten, fa11a08, fb73f10, fc83f12, fd16b10, fk90e11, si:bz1g13.4, wu:fa11a08, wu:fb73f10, wu:fc83f12, wu:fd16b10, wu:fk90e11

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits lipid phosphatase activity. Involved in several processes, including lifelong otolith mineralization; phosphatidylinositol dephosphorylation; and regulation of protein kinase B signaling.  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu1435 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018072Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018073Tg Transgenic Insertion Unknown Unknown DNA
    sa17852 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44756 Point Mutation Unknown Unknown ENU
    Targeting reagents:
    DISEASE ASSOCIATED WITH ptenb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Bannayan-Riley-Ruvalcaba syndrome Cowden syndrome 1 158350
    Lhermitte-Duclos syndrome 158350
    macrocephaly-autism syndrome Macrocephaly/autism syndrome 605309
    prostate cancer Prostate cancer, somatic 176807
    {Glioma susceptibility 2} 613028
    {Meningioma} 607174
    DISEASE ASSOCIATED WITH ptenb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphatidylinositol dephosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function lipid phosphatase activity (more)
    GO Terms (all 26)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ptenb-201 (1) 1947
    ptenb-202 (1) 3380
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM ptenb No data available
    MARKER RELATIONSHIPS
    ptenbContained in: [BAC] RP71-1G13 (1) (order this)
    ptenbEncodes: [EST] fa11a08, fb73f10, fc83f12, fd16b10, fk90e11, IMAGE:7163207 (1) (order this)
    [cDNA] MGC:123112 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001822 (1) 2602bp
    Genomic GenBank:AL731788 (1) 165909bp
    Select Tool
    Polypeptide UniProtKB:Q6TGR5 (1) 422aa
    Sequence Clusters UniGene:150341 (1)
    Sequence Information (all 28)
    ORTHOLOGY for ptenb (Chr: 12)
    CITATIONS (63)