ZFIN is now using GRCz12tu for Genomic Data
Gene
hectd1
- ID
- ZDB-GENE-030616-153
- Name
- HECT domain containing 1
- Symbol
- hectd1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein polyubiquitination. Predicted to act upstream of or within protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be active in nuclear speck. Orthologous to human HECTD1 (HECT domain E3 ubiquitin protein ligase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000569 | HECT domain |
| Domain | IPR010606 | Mib-herc2 |
| Domain | IPR012919 | SUN domain |
| Domain | IPR041200 | FKBP3, basic tilted helix bundle domain |
| Family | IPR045322 | E3 ubiquitin-protein ligase HECTD1/TRIP12-like |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR035983 | HECT, E3 ligase catalytic domain |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Homologous_superfamily | IPR037252 | Mib/herc2 domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Armadillo-like helical | Armadillo-type fold | E3 ubiquitin-protein ligase HECTD1/TRIP12-like | FKBP3, basic tilted helix bundle domain | Galactose-binding-like domain superfamily | HECT domain | HECT, E3 ligase catalytic domain | Mib-herc2 | Mib/herc2 domain superfamily | SUN domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AJX0 | InterPro | 2585 | ||||||||||||
| UniProtKB:A0A8M3AUD5 | InterPro | 2523 | ||||||||||||
| UniProtKB:A0A0R4IGL6 | InterPro | 2509 | ||||||||||||
| UniProtKB:Q8JFV5 | InterPro | 2576 | ||||||||||||
| UniProtKB:A0A8M3AJX5 | InterPro | 1334 | ||||||||||||
| UniProtKB:A0A8M3AJ23 | InterPro | 2524 | ||||||||||||
| UniProtKB:A0A8M3ARF8 | InterPro | 2538 | ||||||||||||
| UniProtKB:A0A2R8PW57 | InterPro | 2570 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hectd1-201
(1)
|
Ensembl | 9,030 nt | ||
| mRNA |
hectd1-205
(1)
|
Ensembl | 745 nt | ||
| mRNA |
hectd1-206
(1)
|
Ensembl | 566 nt | ||
| mRNA |
hectd1-208
(1)
|
Ensembl | 8,669 nt | ||
| mRNA |
hectd1-209
(1)
|
Ensembl | 7,971 nt | ||
| mRNA |
hectd1-210
(1)
|
Ensembl | 8,154 nt | ||
| ncRNA |
hectd1-002
(1)
|
Ensembl | 1,761 nt | ||
| ncRNA |
hectd1-003
(1)
|
Ensembl | 1,221 nt | ||
| ncRNA |
hectd1-004
(1)
|
Ensembl | 731 nt | ||
| ncRNA |
hectd1-007
(1)
|
Ensembl | 587 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers