Gene
erlec1
- ID
- ZDB-GENE-030521-15
- Name
- endoplasmic reticulum lectin 1
- Symbol
- erlec1 Nomenclature History
- Previous Names
-
- sb:cb309
- wu:fi15g10
- zgc:55819
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to enable carbohydrate binding activity. Predicted to be involved in retrograde protein transport, ER to cytosol. Predicted to act upstream of or within ERAD pathway. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum lumen. Is expressed in several structures, including anterior axial hypoblast; axial mesoderm; axis; hatching gland; and otic placode. Orthologous to human ERLEC1 (endoplasmic reticulum lectin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb309 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| mnu107 | Allele with one deletion | Unknown | Unknown | CRISPR |
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Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Mannose-6-phosphate receptor binding domain superfamily | MRH domain | Protein OS-9-like | Protein OS9-like domain |
|---|---|---|---|---|---|---|
| UniProtKB:Q803G0 | InterPro | 482 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
erlec1-201
(1)
|
Ensembl | 2,144 nt | ||
| mRNA |
erlec1-202
(1)
|
Ensembl | 2,009 nt | ||
| mRNA |
erlec1-203
(1)
|
Ensembl | 2,266 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-101F17 | ZFIN Curated Data | |
| Contained in | BAC | CH73-364A9 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-97K15 | ZFIN Curated Data | |
| Encodes | EST | cb309 | Thisse et al., 2001 | |
| Encodes | EST | fi15g10 | ||
| Encodes | cDNA | MGC:55819 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:174130 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_199432 (1) | 2102 nt | ||
| Genomic | GenBank:BX511188 (1) | 233525 nt | ||
| Polypeptide | UniProtKB:Q803G0 (1) | 482 aa |
- Fung, C., Wilding, B., Schittenhelm, R.B., Bryson-Richardson, R.J., Bird, P.I. (2023) Expression of the Z Variant of α1-Antitrypsin Suppresses Hepatic Cholesterol Biosynthesis in Transgenic Zebrafish. International Journal of Molecular Sciences. 24(3):
- Maugars, G., Dufour, S. (2015) Demonstration of the Coexistence of Duplicated LH Receptors in Teleosts, and Their Origin in Ancestral Actinopterygians. PLoS One. 10:e0135184
- Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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