ZFIN ID: ZDB-GENE-030515-2
Gene Name: PIN2 (TERF1) interacting telomerase inhibitor 1
Gene Symbol: pinx1    Nomenclature History

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Previous Names: cb342 (1), LPTS (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Exhibits telomerase inhibitor activity. Localizes to nucleolus. Is expressed in several structures, including digestive system; fin; mesoderm; nervous system; and pleuroperitoneal region. Orthologous to human PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1).
Genome Resources: Alliance (1),  Gene:368253 (1),  Ensembl(GRCz11):ENSDARG00000023532 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23666 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-pinx1
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pinx1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pinx1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component nucleolus (more)
    Molecular Function telomerase inhibitor activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pinx1-201 (1)    Ensembl 1814
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pinx1 No data available
    MARKER RELATIONSHIPS
    pinx1 Contained in: [BAC] DKEY-155D18 (order this)
    pinx1 Encodes: [EST] cb342 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001013265 (1) 1089 nt
    Genomic GenBank:BX510941 (1) 183212 nt
    Select Tool
    Polypeptide UniProtKB:Q5QGN4 (1) 355 aa
    Sequence Information (all 20)
    ORTHOLOGY for pinx1 ( Chr: 20 )
    CITATIONS (21)