Gene

tshba

ID
ZDB-GENE-030513-3
Name
thyroid stimulating hormone subunit beta a
Symbol
tshba Nomenclature History
Previous Names
  • tshb (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Is predicted to contribute to hormone activity. Predicted to be involved in G protein-coupled receptor signaling pathway and hormone-mediated signaling pathway. Predicted to localize to cytoplasm and extracellular space. Is expressed in adenohypophyseal placode; head; and hypophysis. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 4 and hypothyroidism. Orthologous to human TSHB (thyroid stimulating hormone subunit beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
36 figures from 26 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tshba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital nongoitrous hypothyroidism 4 Alliance Hypothyroidism, congenital, nongoitrous 4 275100
Associated With tshba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018245 Gonadotropin, beta subunit, conserved site
Domain IPR006208 Glycoprotein hormone subunit beta
Family IPR001545 Gonadotropin, beta subunit
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Cystine-knot cytokine Glycoprotein hormone subunit beta Gonadotropin, beta subunit Gonadotropin, beta subunit, conserved site
UniProtKB:Q801K4 148
UniProtKB:B3DJU0 148
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations