Gene
prl
- ID
- ZDB-GENE-030513-1
- Name
- prolactin
- Symbol
- prl Nomenclature History
- Previous Names
-
- prl1 (1)
- zgc:110500
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable hormone activity. Acts upstream of or within monoatomic ion homeostasis; multicellular organismal response to stress; and negative regulation of apoptotic process. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including adenohypophyseal placode; female organism; hypophysis; male organism; and peptide hormone secreting cell. Human ortholog(s) of this gene implicated in carotid artery disease and impulse control disorder. Orthologous to human PRL (prolactin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 61 figures from 34 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Four-helical cytokine-like, core | Somatotropin hormone, conserved site | Somatotropin/prolactin |
|---|---|---|---|---|---|
| UniProtKB:Q569P7 | InterPro | 210 |
Interactions and Pathways
Plasmids
No data available