Gene
prl
- ID
- ZDB-GENE-030513-1
- Name
- prolactin
- Symbol
- prl Nomenclature History
- Previous Names
-
- prl1 (1)
- zgc:110500
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Is predicted to enable hormone activity. Involved in positive regulation of cell population proliferation; positive regulation of receptor signaling pathway via JAK-STAT; and response to nutrient levels. Acts upstream of or within ion homeostasis; multicellular organismal response to stress; and negative regulation of apoptotic process. Predicted to be located in extracellular region. Is expressed in adenohypophyseal placode; female organism; hypophysis; male organism; and peptide hormone secreting cell. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human PRL (prolactin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 57 figures from 31 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Four-helical cytokine-like, core | Somatotropin hormone, conserved site | Somatotropin/prolactin |
|---|---|---|---|---|
|
UniProtKB:Q569P7
|
210 |
Interactions and Pathways
Plasmids
No data available