ZFIN is now using GRCz12tu for Genomic Data
Gene
bmal1b
- ID
- ZDB-GENE-030408-1
- Name
- basic helix-loop-helix ARNT like 1b
- Symbol
- bmal1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables chromatin binding activity. Contributes to DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in circadian regulation of gene expression and positive regulation of transcription by RNA polymerase II. Acts upstream of or within photoperiodism and positive regulation of gene expression. Located in chromatin. Part of CLOCK-BMAL transcription complex. Is expressed in brain; heart; liver; muscle; and retina. Human ortholog(s) of this gene implicated in alcohol dependence and bipolar disorder. Orthologous to human BMAL1 (basic helix-loop-helix ARNT like 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000014 | PAS domain |
| Domain | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
| Domain | IPR013767 | PAS fold |
| Family | IPR001067 | Nuclear translocator |
| Family | IPR050933 | Circadian Clock Transcription Factors |
| Homologous_superfamily | IPR035965 | PAS domain superfamily |
| Homologous_superfamily | IPR036638 | Helix-loop-helix DNA-binding domain superfamily |
| Repeat | IPR001610 | PAC motif |
Domain Details Per Protein
| Protein | Additional Resources | Length | Circadian Clock Transcription Factors | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Nuclear translocator | PAC motif | PAS domain | PAS domain superfamily | PAS fold |
|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PNL9 | InterPro | 671 | ||||||||
| UniProtKB:A0A8M3BBD8 | InterPro | 653 | ||||||||
| UniProtKB:Q8JIG1 | InterPro | 622 | ||||||||
| UniProtKB:A0A8M2BE61 | InterPro | 676 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
arntl1b-201
(1)
|
Ensembl | 2,400 nt | ||
| mRNA |
arntl1b-203
(1)
|
Ensembl | 1,869 nt | ||
| ncRNA |
arntl1b-003
(1)
|
Ensembl | 1,210 nt | ||
| ncRNA |
arntl1b-004
(1)
|
Ensembl | 815 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers