Gene

prdx2

ID
ZDB-GENE-030326-2
Name
peroxiredoxin 2
Symbol
prdx2 Nomenclature History
Previous Names
  • prdx1 (1)
  • cb58 (1)
  • NKEF-B (1)
  • wu:fq19b09
  • zgc:92891
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have thioredoxin peroxidase activity. Predicted to be involved in several processes, including cell redox homeostasis; hydrogen peroxide catabolic process; and removal of superoxide radicals. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in methylmalonic aciduria and homocystinuria type cblC. Is expressed in several structures, including digestive system; nervous system; neural tube; presumptive blood; and ventral mesoderm. Orthologous to several human genes including PRDX2 (peroxiredoxin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prdx2 Human Ortholog
No data available
Associated With prdx2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Domain IPR013766 Thioredoxin domain
Domain IPR019479 Peroxiredoxin, C-terminal
Family IPR024706 Peroxiredoxin, AhpC-type
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant Peroxiredoxin, AhpC-type Peroxiredoxin, C-terminal Thioredoxin domain Thioredoxin-like superfamily
UniProtKB:Q6DGJ6 197
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations