Gene
p2rx7
- ID
- ZDB-GENE-030319-6
- Name
- purinergic receptor P2X, ligand-gated ion channel, 7
- Symbol
- p2rx7 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Exhibits extracellularly ATP-gated cation channel activity. Involved in calcium ion import across plasma membrane and macrophage chemotaxis. Localizes to plasma membrane. Is expressed in brain; midbrain hindbrain boundary; pronephric duct; and spinal cord. Orthologous to human P2RX7 (purinergic receptor P2X 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu706 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Ogryzko et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P2X7 purinoceptor | P2X purinoreceptor | P2X purinoreceptor 7, intracellular domain | P2X purinoreceptor extracellular domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q7SZM2
|
596 |
Interactions and Pathways
No data available
Plasmids
No data available