Gene

quo

ID
ZDB-GENE-030131-9944
Name
quattro
Symbol
quo Nomenclature History
Previous Names
  • cb9 (1)
  • fb97g10 (1)
  • sb:cb9 (1)
  • wu:fb97g10 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity. Involved in animal organ morphogenesis and mesoderm morphogenesis. Is expressed in several structures, including Kupffer's vesicle; anterior axial hypoblast; forerunner cell group; mesoderm; and nervous system. Orthologous to human KIAA1755 (KIAA1755).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With quo Human Ortholog
No data available
Associated With quo Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000219 Dbl homology (DH) domain
Domain IPR001849 Pleckstrin homology domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR035899 Dbl homology (DH) domain superfamily
Domain Details Per Protein
Protein Length Dbl homology (DH) domain Dbl homology (DH) domain superfamily PH-like domain superfamily Pleckstrin homology domain
UniProtKB:A0A2R8QD21 1989
UniProtKB:F1RDN8 1987
UniProtKB:Q6DN89 1989
UniProtKB:X1WBU3 1991
UniProtKB:A0A2R8QQC5 1949
UniProtKB:B3DH45 1990
UniProtKB:A0A2R8QLC3 1988
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Note
Woods, et al. (2005. Genome Res. 15:1307-1314.) report this gene to be the ortholog of human PLEKHG4 based on amino acid similarity. Subsequent analysis suggests it is the ortholog of human KIAA1755 and mouse D630003M21Rik based on amino acid similarity and conserved synteny.
Citations