Gene

sipa1l1

ID

ZDB-GENE-030131-9909

Name

signal-induced proliferation-associated 1 like 1

Symbol

sipa1l1 Nomenclature History

Previous Names

cb600 (1)
id:ibd5092
sb:cb600
si:ch211-106p8.1
wu:fc43g06 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable GTPase activator activity. Predicted to act upstream of or within regulation of small GTPase mediated signal transduction. Predicted to be active in cytoplasm. Is expressed in several structures, including axis; central nervous system; midbrain neural keel; neural plate; and tail bud. Orthologous to human SIPA1L1 (signal induced proliferation associated 1 like 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb600 (24 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sipa1l1 Human Ortholog

No data available

Associated With sipa1l1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000331	Rap/Ran-GAP domain
Domain	IPR001478	PDZ domain
Domain	IPR021818	Signal-induced proliferation-associated 1-like protein, C-terminal
Family	IPR050989	Rap1/Ran GTPase-activating
Homologous_superfamily	IPR035974	Rap/Ran-GAP superfamily
Homologous_superfamily	IPR036034	PDZ superfamily

Domain Details Per Protein

Protein	Length	PDZ domain	PDZ superfamily	Rap1/Ran GTPase-activating	Rap/Ran-GAP domain	Rap/Ran-GAP superfamily	Signal-induced proliferation-associated 1-like protein, C-terminal
UniProtKB:Q5TYS4 InterPro	1794
UniProtKB:A0A8M3AKY4 InterPro	1787
UniProtKB:A0A8M3ATB4 InterPro	1789
UniProtKB:A0A2R8PWT8 InterPro	1743
UniProtKB:A0A8M3AWC2 InterPro	1793
UniProtKB:A0A8M9P2P0 InterPro	1776
UniProtKB:A0A8M3B485 InterPro	1783

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sipa1l1-201 (1) Ensembl	Ensembl	8,488 nt	Select Tool ZFIN BLAST
mRNA	sipa1l1-202 (1) Ensembl	Ensembl	5,766 nt	Select Tool ZFIN BLAST
mRNA	sipa1l1-203 (1) Ensembl	Ensembl	5,331 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations