Gene
cpox
- ID
- ZDB-GENE-030131-9884
- Name
- coproporphyrinogen oxidase
- Symbol
- cpox Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable coproporphyrinogen oxidase activity. Acts upstream of or within hemoglobin biosynthetic process. Predicted to be active in cytoplasm. Is expressed in hematopoietic system; kidney; mesoderm; presumptive blood; and ventral mesenchyme. Human ortholog(s) of this gene implicated in hereditary coproporphyria and liver disease. Orthologous to human CPOX (coproporphyrinogen oxidase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb535 (6 images)
- IMAGE:7156501 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary coproporphyria | Alliance | Coproporphyria | 121300 |
| Harderoporphyria | 618892 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Coproporphyrinogen III oxidase, aerobic | Coproporphyrinogen III oxidase, conserved site | Oxygen-dependent coproporphyrinogen III oxidase superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q05AK3 | InterPro | 449 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available