Gene

ptprk

ID

ZDB-GENE-030131-9834

Name

protein tyrosine phosphatase receptor type K

Symbol

ptprk Nomenclature History

Previous Names

cb424 (1)
sb:cb424
si:dkey-126h10.3
wu:fa06f08

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable histone H2AXY142 phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity; and protein tyrosine phosphatase activity, metal-dependent. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in membrane. Is expressed in several structures, including cardiovascular system; digestive system; immature eye; musculature system; and nervous system. Orthologous to human PTPRK (protein tyrosine phosphatase receptor type K).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb424 (21 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Casar et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptprk Human Ortholog

No data available

Associated With ptprk Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR000998	MAM domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR003599	Immunoglobulin domain subtype
Domain	IPR003961	Fibronectin type III
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013151	Immunoglobulin-like beta-sandwich domain
Family	IPR050348	Protein-Tyrosine Phosphatase
Family	IPR051622	Receptor-type Tyrosine-protein Phosphatases
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR036116	Fibronectin type III superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PPR4	InterPro	1479
UniProtKB:A0A8M9PT51	InterPro	1463
UniProtKB:A0A8M9PHP0	InterPro	1490
UniProtKB:A0A8M9PC34	InterPro	1447
UniProtKB:A0A8M9PT46	InterPro	1484
UniProtKB:A0A8M9P2V1	InterPro	1459
UniProtKB:A0A8M9PT41	InterPro	1497
UniProtKB:A0A8M9PHP6	InterPro	1467
UniProtKB:A0A8M9P2U5	InterPro	1494
UniProtKB:A0A8M9PPQ9	InterPro	1496
UniProtKB:A0A8M9PC25	InterPro	1492
UniProtKB:A0A8M9PHN7	InterPro	1500
UniProtKB:A0A8M9PT56	InterPro	1457
UniProtKB:A0A8M9PC30	InterPro	1473
UniProtKB:A0A8M9PHP9	InterPro	1441
UniProtKB:A0A8M9P2U7	InterPro	1474
UniProtKB:A0AB32TAQ7	InterPro	1470
UniProtKB:A0AB32TAZ4	InterPro	1451
UniProtKB:A0AB32TCD8	InterPro	1449
UniProtKB:A0AB32TE97	InterPro	1443

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ptprk-201 (1) Ensembl	Ensembl	4,547 nt	Select Tool ZFIN BLAST
mRNA	ptprk-202 (1) Ensembl	Ensembl	3,595 nt	Select Tool ZFIN BLAST
mRNA	ptprk-203 (1) Ensembl	Ensembl	604 nt	Select Tool ZFIN BLAST
mRNA	ptprk-205 (1) Ensembl	Ensembl	3,384 nt	Select Tool ZFIN BLAST
ncRNA	ptprk-002 (1) Ensembl	Ensembl	845 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations