Gene
ptprk
- ID
- ZDB-GENE-030131-9834
- Name
- protein tyrosine phosphatase receptor type K
- Symbol
- ptprk Nomenclature History
- Previous Names
-
- cb424 (1)
- sb:cb424
- si:dkey-126h10.3
- wu:fa06f08
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to act upstream of or within dephosphorylation. Predicted to be located in membrane. Is expressed in several structures, including cardiovascular system; digestive system; immature eye; musculature system; and nervous system. Orthologous to human PTPRK (protein tyrosine phosphatase receptor type K).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb424 (21 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Casar et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016130 | Protein-tyrosine phosphatase, active site |
| Domain | IPR000242 | Tyrosine-specific protein phosphatase, PTPase domain |
| Domain | IPR000387 | Tyrosine-specific protein phosphatases domain |
| Domain | IPR000998 | MAM domain |
| Domain | IPR003595 | Protein-tyrosine phosphatase, catalytic |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013151 | Immunoglobulin-like beta-sandwich domain |
| Family | IPR051622 | Receptor-type Tyrosine-protein Phosphatases |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR029021 | Protein-tyrosine phosphatase-like |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Concanavalin A-like lectin/glucanase domain superfamily | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin-like beta-sandwich domain | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | MAM domain | Protein-tyrosine phosphatase, active site | Protein-tyrosine phosphatase, catalytic | Protein-tyrosine phosphatase-like | Receptor-type Tyrosine-protein Phosphatases | Tyrosine-specific protein phosphatase, PTPase domain | Tyrosine-specific protein phosphatases domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PPR4
|
1479 | |||||||||||||||
|
UniProtKB:A0A8M9PT51
|
1463 | |||||||||||||||
|
UniProtKB:A0A8M9PHP0
|
1490 | |||||||||||||||
|
UniProtKB:A0A8M9PC34
|
1447 | |||||||||||||||
|
UniProtKB:A0A8M9PT46
|
1484 | |||||||||||||||
|
UniProtKB:A0A8M9P2V1
|
1459 | |||||||||||||||
|
UniProtKB:A0A8M9PT41
|
1497 | |||||||||||||||
|
UniProtKB:A0A8M9PHP6
|
1467 | |||||||||||||||
|
UniProtKB:A0A8M9P2U5
|
1494 | |||||||||||||||
|
UniProtKB:A0A8M9PPQ9
|
1496 | |||||||||||||||
|
UniProtKB:A0A8M9PC25
|
1492 | |||||||||||||||
|
UniProtKB:A0A8M9PHN7
|
1500 | |||||||||||||||
|
UniProtKB:A0A8M9PT56
|
1457 | |||||||||||||||
|
UniProtKB:A0A8M9PC30
|
1473 | |||||||||||||||
|
UniProtKB:A0A8M9PHP9
|
1441 | |||||||||||||||
|
UniProtKB:A0A8M9P2U7
|
1474 |
Interactions and Pathways
No data available
Plasmids
No data available