ZFIN ID: ZDB-GENE-030131-9823
Gene Name: laminin, alpha 5
Gene Symbol: lama5    Nomenclature History

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Previous Names: fra (1), cb402 (1), fransen (1), im:7138247, sb:cb402, unm m538, wu:fb81a10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have integrin binding activity. Involved in cell-cell adhesion; fin morphogenesis; and protein localization. Predicted to localize to laminin-5 complex. Is expressed in several structures, including axial mesoderm; endoderm; nervous system; pectoral fin bud; and pharynx. Orthologous to human LAMA5 (laminin subunit alpha 5).
Genome Resources: Alliance (1),  Gene:321243 (1),  Ensembl(GRCz11):ENSDARG00000058543 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la022827Tg Transgenic Insertion Unknown Unknown DNA
la022828Tg Transgenic Insertion Unknown Unknown DNA
m538 Point Mutation Exon 59 Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6725 Point Mutation Unknown Premature Stop ENU
    sa9446 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9662 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13881 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16078 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16193 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16872 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18231 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18267 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24259 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24260 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25193 Point Mutation Unknown Splice Site ENU
    sa29878 Point Mutation Unknown Splice Site ENU
    sa37625 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43917 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43918 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43919 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tc17 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tk219a Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tm55 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tr206b Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-lama5 N/A 1
    MO2-lama5 N/A 1
    MO3-lama5 N/A 6
    DISEASE ASSOCIATED WITH lama5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lama5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell-cell adhesion (more)
    Cellular Component basement membrane (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lama5-201 (1)    Ensembl 11542
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lama5 No data available
    MARKER RELATIONSHIPS
    lama5 Contained in: [BAC] CH73-78G5 (1), DKEY-14P11 (1) (order this), DKEY-204F1 (1) (order this)
    lama5 Encodes: [EST] cb402 (1) (order this), fb81a10 (1) (order this), IMAGE:7138247 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001039171 (1) 11565 nt
    Genomic GenBank:BX470099 (1) 199831 nt
    Select Tool
    Polypeptide UniProtKB:D7PSA0 (1) 3664 aa
    Sequence Information (all 24)
    ORTHOLOGY for lama5 ( Chr: 23 )
    CITATIONS (54)