Gene

rspo3

ID
ZDB-GENE-030131-9814
Name
R-spondin 3
Symbol
rspo3 Nomenclature History
Previous Names
  • cb387 (1)
  • sb:cb387
  • wu:fa13e08
  • zgc:162040
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have heparin binding activity. Involved in negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification; negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation; and posterior lateral line neuromast development. Predicted to localize to extracellular region. Is expressed in several structures, including digestive system; endoderm; forebrain neural keel; nervous system; and presumptive telencephalon. Orthologous to human RSPO3 (R-spondin 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rspo3 Human Ortholog
No data available
Associated With rspo3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR043601 R-spondin, Fu-CRD domain
Family IPR042994 R-spondin-3
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Repeat IPR006212 Furin-like repeat
Domain Details Per Protein
Protein Length Furin-like repeat Growth factor receptor cysteine-rich domain superfamily R-spondin-3 R-spondin, Fu-CRD domain Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:M5AN53 317
UniProtKB:F1R6D4 317
UniProtKB:Q5R328 317
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations