Gene

rspo3

ID
ZDB-GENE-030131-9814
Name
R-spondin 3
Symbol
rspo3 Nomenclature History
Previous Names
  • cb387 (1)
  • sb:cb387
  • wu:fa13e08
  • zgc:162040
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to enable frizzled binding activity. Acts upstream of or within several processes, including pectoral fin development; posterior lateral line neuromast development; and regulation of odontogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cranium; digestive system; endoderm; forebrain neural keel; and nervous system. Orthologous to human RSPO3 (R-spondin 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa14295Allele with one point mutationUnknownPremature StopENU
zf3495Allele with one deletionExon 2UnknownCRISPR
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Sequence Targeting Reagents
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Human Disease
Associated With rspo3 Human Ortholog
No data available
Associated With rspo3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR043601 R-spondin, Fu-CRD domain
Domain IPR044004 Spondin-like TSP1 domain
Family IPR051514 R-spondin domain-containing protein
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
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Domain Details Per Protein
Protein Additional Resources Length Furin-like repeat Growth factor receptor cysteine-rich domain superfamily R-spondin domain-containing protein R-spondin, Fu-CRD domain Spondin-like TSP1 domain Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:A0A8M2B4I7 InterPro 248
UniProtKB:Q5R328 InterPro 317
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 16
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rspo3-201 (1) Ensembl 2,194 nt
ncRNA rspo3-002 (1) Ensembl 629 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-195P4ZFIN Curated Data
Contained inBACDKEY-242E21ZFIN Curated Data
EncodesESTcb387Thisse et al., 2001
EncodesESTfa13e08ZFIN Curated Data
EncodescDNAMGC:162040ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRSPO36
Phylogenetic tree (2)
Conserved genome location (synteny) (1)
Amino acid sequence comparison (4)
MouseRspo310
Amino acid sequence comparison (3)
Phylogenetic tree (2)
Citations
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