Gene
mbd3b
- ID
- ZDB-GENE-030131-9792
- Name
- methyl-CpG binding domain protein 3b
- Symbol
- mbd3b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have methyl-CpG binding activity. Involved in definitive hemopoiesis and hematopoietic progenitor cell differentiation. Predicted to localize to nucleus. Is expressed in several structures, including Kupffer's vesicle; central nervous system; forerunner cell group; midbrain neural keel; and retina. Orthologous to human MBD3 (methyl-CpG binding domain protein 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb99 (8 images)
- cb357 (11 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Binding_site | IPR000048 | IQ motif, EF-hand binding site |
Domain | IPR001609 | Myosin head, motor domain |
Domain | IPR001739 | Methyl-CpG DNA binding |
Domain | IPR002710 | Dilute domain |
Domain | IPR025884 | Methyl-CpG binding protein 2/3, C-terminal domain |
Domain | IPR032343 | Methyl-CpG-binding domain protein 2/3, p55-binding region |
Domain | IPR036103 | Class V myosin, motor domain |
Family | IPR037965 | Methyl-CpG-binding domain protein 3 |
Homologous_superfamily | IPR016177 | DNA-binding domain superfamily |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
Protein | Length | Class V myosin, motor domain | Dilute domain | DNA-binding domain superfamily | IQ motif, EF-hand binding site | Kinesin motor domain superfamily | Methyl-CpG-binding domain protein 2/3, p55-binding region | Methyl-CpG-binding domain protein 3 | Methyl-CpG binding protein 2/3, C-terminal domain | Methyl-CpG DNA binding | Myosin head, motor domain | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:F1QL92
|
242 | |||||||||||
UniProtKB:Q1LXS3
|
184 | |||||||||||
UniProtKB:A0A2R8QPC3
|
265 | |||||||||||
UniProtKB:A0A0R4IA78
|
265 | |||||||||||
UniProtKB:Q7ZZR0
|
242 | |||||||||||
UniProtKB:F1QPJ2
|
401 | |||||||||||
UniProtKB:F1QXS0
|
1031 |
Interactions and Pathways
No data available
Plasmids
No data available