Gene

mbd3b

ID
ZDB-GENE-030131-9792
Name
methyl-CpG binding domain protein 3b
Symbol
mbd3b Nomenclature History
Previous Names
  • cb357 (1)
  • cb99 (1)
  • sb:cb357
  • sb:cb99
  • wu:fc41c05
  • zgc:111851
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have several functions, including ATP binding activity; actin filament binding activity; and motor activity. Involved in definitive hemopoiesis and hematopoietic progenitor cell differentiation. Predicted to localize to myosin complex and nucleus. Is expressed in several structures, including Kupffer's vesicle; central nervous system; forerunner cell group; midbrain neural keel; and retina. Orthologous to human MBD3 (methyl-CpG binding domain protein 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mbd3b Human Ortholog
No data available
Associated With mbd3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR001609 Myosin head, motor domain
Domain IPR001739 Methyl-CpG DNA binding
Domain IPR002710 Dilute domain
Domain IPR025884 Methyl-CpG binding protein 2/3, C-terminal domain
Domain IPR032343 Methyl-CpG-binding domain protein 2/3, p55-binding region
Domain IPR036103 Class V myosin, motor domain
Family IPR037965 Methyl-CpG-binding domain protein 3
Homologous_superfamily IPR008989 Myosin S1 fragment, N-terminal
Homologous_superfamily IPR016177 DNA-binding domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length Class V myosin, motor domain Dilute domain DNA-binding domain superfamily IQ motif, EF-hand binding site Kinesin motor domain superfamily Methyl-CpG-binding domain protein 2/3, p55-binding region Methyl-CpG-binding domain protein 3 Methyl-CpG binding protein 2/3, C-terminal domain Methyl-CpG DNA binding Myosin head, motor domain Myosin S1 fragment, N-terminal P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q7ZZR0 242
UniProtKB:F1QXS0 1031
UniProtKB:A0A0R4IA78 265
UniProtKB:F1QPJ2 401
UniProtKB:A0A2R8QPC3 265
UniProtKB:Q1LXS3 184
UniProtKB:F1QL92 242
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations