Gene
cct5
- ID
- ZDB-GENE-030131-977
- Name
- chaperonin containing TCP1, subunit 5 (epsilon)
- Symbol
- cct5 Nomenclature History
- Previous Names
-
- TCP-1 epsilon (1)
- unm tf212
- unm_tf212
- wu:fb54h08
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable unfolded protein binding activity. Acts upstream of or within retina layer formation and skeletal muscle thin filament assembly. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Is expressed in several structures, including epidermis; nervous system; pharyngeal arch 3-7 skeleton; proliferative region; and yolk syncytial layer. Orthologous to human CCT5 (chaperonin containing TCP1 subunit 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7147715 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ?Neuropathy, hereditary sensory, with spastic paraplegia | 256840 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR002194 | Chaperonin TCP-1, conserved site |
| Family | IPR002423 | Chaperonin Cpn60/GroEL/TCP-1 family |
| Family | IPR012718 | T-complex protein 1, epsilon subunit |
| Family | IPR017998 | Chaperone tailless complex polypeptide 1 (TCP-1) |
| Family | IPR053374 | TCP-1 chaperonin-containing T-complex |
| Family | IPR054827 | Thermosome subunit alpha |
| Homologous_superfamily | IPR027409 | GroEL-like apical domain superfamily |
| Homologous_superfamily | IPR027410 | TCP-1-like chaperonin intermediate domain superfamily |
| Homologous_superfamily | IPR027413 | GroEL-like equatorial domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Chaperone tailless complex polypeptide 1 (TCP-1) | Chaperonin Cpn60/GroEL/TCP-1 family | Chaperonin TCP-1, conserved site | GroEL-like apical domain superfamily | GroEL-like equatorial domain superfamily | T-complex protein 1, epsilon subunit | TCP-1 chaperonin-containing T-complex | TCP-1-like chaperonin intermediate domain superfamily | Thermosome subunit alpha |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q6NVI6 | InterPro | 541 |
Interactions and Pathways
No data available
Plasmids
No data available