Gene
akap12b
- ID
- ZDB-GENE-030131-9753
- Name
- A kinase (PRKA) anchor protein 12b
- Symbol
- akap12b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable calmodulin binding activity and protein kinase A binding activity. Acts upstream of or within several processes, including Kupffer's vesicle development; bleb assembly; and negative regulation of Rho protein signal transduction. Located in perinuclear region of cytoplasm. Is expressed in several structures, including cardiovascular system; germ ring; mesoderm; nervous system; and tail bud. Human ortholog(s) of this gene implicated in chronic kidney disease; colorectal carcinoma; and juvenile myelomonocytic leukemia. Orthologous to human AKAP12 (A-kinase anchoring protein 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb27 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 12 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif | A-kinase anchor protein 12 |
|---|---|---|---|---|
| UniProtKB:A0A0R4IC31 | InterPro | 1596 | ||
| UniProtKB:F2Z4T4 | InterPro | 1533 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
akap12b-201
(1)
|
Ensembl | 648 nt | ||
| mRNA |
akap12b-202
(1)
|
Ensembl | 6,450 nt | ||
| mRNA |
akap12b-203
(1)
|
Ensembl | 7,749 nt | ||
| mRNA |
akap12b-204
(1)
|
Ensembl | 9,480 nt | ||
| mRNA |
akap12b-205
(1)
|
Ensembl | 7,621 nt |
Interactions and Pathways
No data available
Plasmids
No data available