ZFIN ID: ZDB-GENE-030131-9753
Gene Name: A kinase (PRKA) anchor protein 12b
Gene Symbol: akap12b    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: akap12, cb27 (1), fb72g12, gravin (1), id:ibd1202, sb:cb27, si:ch73-192g21.1, wu:fb72g12, wu:fc21c03

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have protein kinase A binding activity. Involved in several processes, including bleb assembly; negative regulation of Rho protein signal transduction; and slow muscle cell migration. Localizes to perinuclear region of cytoplasm. Is expressed in several structures, including cardiovascular system; germ ring; mesoderm; nervous system; and tail bud. Human ortholog(s) of this gene implicated in chronic kidney disease; colorectal carcinoma; and juvenile myelomonocytic leukemia. Orthologous to human AKAP12 (A-kinase anchoring protein 12).
Genome Resources: Alliance (1),  Gene:567365 (1),  Ensembl(GRCz11):ENSDARG00000055678 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb67 Indel Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb68 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb69 Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • la010281Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa72 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15047 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43450 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43451 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-akap12b 1
    MO1-akap12b N/A 3
    MO2-akap12b N/A 4
    MO3-akap12b N/A 1
    MO4-akap12b N/A 2
    MO5-akap12b N/A 2
    DISEASE ASSOCIATED WITH akap12b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH akap12b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell morphogenesis (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein kinase A binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA akap12b-201 (1)    Ensembl 648
    akap12b-202 (1)    Ensembl 6450
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM akap12b No data available
    MARKER RELATIONSHIPS
    akap12b Contained in: [BAC] CH73-109I14 (1), CH73-192G21 (1), DKEY-147L14 (1) (order this)
    akap12b Contains: [SNP] rs3729026 (1)
    [STS] chunp30253
    akap12b Encodes: [EST] cb27 (1) (order this), fb72g12 (1), fc21c03, ibd1202, wz11325, wz12504 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001098184 (1) 4602 nt
    Genomic GenBank:CR926887 184926 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IC31 (1) 1596 aa
    Sequence Information (all 30)
    ORTHOLOGY for akap12b ( Chr: 20 )
    CITATIONS (39)