Community Action Needed: Please respond to the NIH RFI
Gene

eif5

ID
ZDB-GENE-030131-975
Name
eukaryotic translation initiation factor 5
Symbol
eif5 Nomenclature History
Previous Names
  • fb37c12
  • fb54h04
  • wu:fb37c12
  • wu:fb54h04
  • zgc:77026 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to enable GDP-dissociation inhibitor activity; eukaryotic initiation factor eIF2 binding activity; and translation initiation factor activity. Predicted to be involved in formation of cytoplasmic translation initiation complex and formation of translation preinitiation complex. Predicted to act upstream of or within translational initiation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytosol. Is expressed in lens. Orthologous to human EIF5 (eukaryotic translation initiation factor 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eif5 Human Ortholog
No data available
Associated With eif5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002735 Translation initiation factor IF2/IF5
Domain IPR003307 W2 domain
Homologous_superfamily IPR016021 MIF4G-like domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR016189 Translation initiation factor IF2/IF5, N-terminal
Homologous_superfamily IPR016190 Translation initiation factor IF2/IF5, zinc-binding
Domain Details Per Protein
Protein Length Armadillo-type fold MIF4G-like domain superfamily Translation initiation factor IF2/IF5 Translation initiation factor IF2/IF5, N-terminal Translation initiation factor IF2/IF5, zinc-binding W2 domain
UniProtKB:R4GEE0 109
UniProtKB:A0A2R8QLZ8 435
UniProtKB:Q7ZWA9 429
UniProtKB:Q5RG39 146
UniProtKB:R4GDN5 124
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations