Gene

thumpd3

ID

ZDB-GENE-030131-9745

Name

THUMP domain containing 3

Symbol

thumpd3 Nomenclature History

Previous Names

cb255 (1)
sb:cb255
zgc:163086 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. Predicted to act upstream of or within methylation. Is expressed in several structures, including alar plate midbrain region; immature eye; mesoderm; musculature system; and nervous system. Orthologous to human THUMPD3 (THUMP domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb255 (14 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With thumpd3 Human Ortholog

No data available

Associated With thumpd3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR053943	Ribosomal RNA large subunit methyltransferase K/L-like, conserved site
Domain	IPR000241	Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain
Domain	IPR004114	THUMP domain
Homologous_superfamily	IPR029063	S-adenosyl-L-methionine-dependent methyltransferase superfamily

Domain Details Per Protein

Protein	Length	Ribosomal RNA large subunit methyltransferase K/L-like, conserved site	Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain	S-adenosyl-L-methionine-dependent methyltransferase superfamily	THUMP domain
UniProtKB:A3KP95 InterPro	477
UniProtKB:E9QJ61 InterPro	482

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	thumpd3-201 (1) Ensembl	Ensembl	1,619 nt	Select Tool ZFIN BLAST
mRNA	thumpd3-202 (1) Ensembl	Ensembl	2,258 nt	Select Tool ZFIN BLAST
mRNA	thumpd3-203 (1) Ensembl	Ensembl	1,619 nt	Select Tool ZFIN BLAST
mRNA	thumpd3-204 (1) Ensembl	Ensembl	1,449 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations