Gene
rap1b
- ID
- ZDB-GENE-030131-9662
- Name
- RAP1B, member of RAS oncogene family
- Symbol
- rap1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Exhibits MAP kinase kinase activity. Involved in chordate embryonic development; convergent extension; and heart development. Localizes to cell-cell junction. Is expressed in several structures, including brain; cardiovascular system; floor plate; hindbrain neural plate; and mesoderm. Orthologous to human RAP1B (RAP1B, member of RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb119 (6 images)
- cb1026 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Thrombocytopenia 11 with multiple congenital anomalies and dysmorphic facies | 620654 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Ras-related protein Rap1 | Small GTPase | Small GTPase, Ras-type | Small GTP-binding domain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6TEN1
|
184 |
Interactions and Pathways
No data available
Plasmids
No data available