Gene

rps6kal

ID

ZDB-GENE-030131-9616

Name

ribosomal protein S6 kinase a, like

Symbol

rps6kal Nomenclature History

Previous Names

wu:fj94b02
zgc:66139 (1)
zmp:0000001068

Type

protein_coding_gene

Location

Chr: 14 Mapping Details/Browsers

Description

Predicted to have ribosomal protein S6 kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. Predicted to localize to cytoplasm and nucleus. Orthologous to human RPS6KA6 (ribosomal protein S6 kinase A6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66139 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rps6kal Human Ortholog

No data available

Associated With rps6kal Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR000961	AGC-kinase, C-terminal
Domain	IPR017892	Protein kinase, C-terminal
Domain	IPR041906	Ribosomal S6 kinase, N-terminal catalytic domain
Family	IPR016239	Ribosomal protein S6 kinase II
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Length	AGC-kinase, C-terminal	Protein kinase, ATP binding site	Protein kinase, C-terminal	Protein kinase domain	Protein kinase-like domain superfamily	Ribosomal protein S6 kinase II	Ribosomal S6 kinase, N-terminal catalytic domain	Serine/threonine-protein kinase, active site
UniProtKB:A0A8M3B8E3 InterPro	578
UniProtKB:Q6PFQ0 InterPro	740
UniProtKB:A0A8M9QGB2 InterPro	507

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rps6kal-201 (1) Ensembl	Ensembl	3,423 nt	Select Tool ZFIN BLAST
mRNA	rps6kal-204 (1) Ensembl	Ensembl	560 nt	Select Tool ZFIN BLAST
ncRNA	rps6kal-005 (1) Ensembl	Ensembl	455 nt	Select Tool ZFIN BLAST
ncRNA	rps6kal-007 (1) Ensembl	Ensembl	536 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations