Gene
camk2b1
- ID
- ZDB-GENE-030131-9588
- Name
- calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
- Symbol
- camk2b1 Nomenclature History
- Previous Names
-
- camk2b
- CAMK2Gb (1)
- fj90d04
- si:dkey-174n20.2
- wu:fj90d04
- zgc:165373
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Enables kinase activity. Predicted to be involved in regulation of neuronal synaptic plasticity; regulation of protein localization to plasma membrane; and signal transduction. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm; neuron projection; and postsynaptic density. Is expressed in several structures, including brain; gut; hatching gland; retina; and trunk. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 54. Orthologous to human CAMK2B (calcium/calmodulin dependent protein kinase II beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 54 | Alliance | Intellectual developmental disorder, autosomal dominant 54 | 617799 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR013543 | Calcium/calmodulin-dependent protein kinase II, association-domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR032710 | NTF2-like domain superfamily |
Domain Details Per Protein
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
camk2b1-201
(1)
|
Ensembl | 5,562 nt | ||
| mRNA |
camk2b1-202
(1)
|
Ensembl | 3,087 nt |
Interactions and Pathways
No data available
Plasmids
No data available