Gene

camk2b1

ID

ZDB-GENE-030131-9588

Name

calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1

Symbol

camk2b1 Nomenclature History

Previous Names

camk2b
CAMK2Gb (1)
fj90d04
si:dkey-174n20.2
wu:fj90d04
zgc:165373

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Enables kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Predicted to be active in cytoplasm and neuron projection. Is expressed in several structures, including brain; gut; hatching gland; retina; and trunk. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 54. Orthologous to human CAMK2B (calcium/calmodulin dependent protein kinase II beta).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With camk2b1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
autosomal dominant intellectual developmental disorder 54	Alliance	Intellectual developmental disorder, autosomal dominant 54	617799

Associated With camk2b1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR013543	Calcium/calmodulin-dependent protein kinase II, association-domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR032710	NTF2-like domain superfamily

Domain Details Per Protein

Protein	Length	Calcium/calmodulin-dependent protein kinase II, association-domain	NTF2-like domain superfamily	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:A0A8M9QE46 InterPro	634
UniProtKB:A0A8M3AZF1 InterPro	644
UniProtKB:A0A8M9Q8S5 InterPro	692
UniProtKB:A0A8M9Q3J8 InterPro	519
UniProtKB:A0A8M9QE54 InterPro	515
UniProtKB:A0A8M3AS35 InterPro	643
UniProtKB:A0A8M9PXV5 InterPro	526
UniProtKB:A0A8M9PKB1 InterPro	650
UniProtKB:A0A8M9PKD0 InterPro	514
UniProtKB:A0A8M9QE51 InterPro	547
UniProtKB:A0A8M9Q8T9 InterPro	546
UniProtKB:E9QDQ2 InterPro	531
UniProtKB:A0A8M3B9H1 InterPro	678
UniProtKB:A0A8M9Q3I6 InterPro	649
UniProtKB:A0A8M9QE58 InterPro	476
UniProtKB:A0A8M3ASA5 InterPro	488
UniProtKB:A0A8M3B9H8 InterPro	500
UniProtKB:A0A8M3B2B8 InterPro	543
UniProtKB:A0A8M9Q8S9 InterPro	660
UniProtKB:A0A8M9PXU3 InterPro	526
UniProtKB:A0A8M3B9H5 InterPro	635
UniProtKB:A0A8M9Q3K8 InterPro	510
UniProtKB:A0A8M9Q8U9 InterPro	349
UniProtKB:A0A8M9PKA6 InterPro	682
UniProtKB:A0A8M3AS95 InterPro	667
UniProtKB:A0A8M9Q8T4 InterPro	623
UniProtKB:A0A8M9QE37 InterPro	693
UniProtKB:A0A8M9QE42 InterPro	661
UniProtKB:A0A8M3AS42 InterPro	509
UniProtKB:A0A8M9Q3I2 InterPro	661
UniProtKB:A0A8M9PXT7 InterPro	565
UniProtKB:A0A8M3ASA1 InterPro	612
UniProtKB:A0A8M9Q3K3 InterPro	487
UniProtKB:A0A8M9PKC4 InterPro	532
UniProtKB:A0A8M3B2C2 InterPro	477
UniProtKB:A0A8M3B2B5 InterPro	655
UniProtKB:A0A8M9PKD4 InterPro	547
UniProtKB:A0A8M9PXT2 InterPro	650
UniProtKB:A0A8M9Q8U4 InterPro	515
UniProtKB:A0A8M9PXS6 InterPro	681
UniProtKB:A0A8M3AZF7 InterPro	520
UniProtKB:A0A8M9PKB9 InterPro	611
UniProtKB:A0A8M9Q3H8 InterPro	693
UniProtKB:A0A8M9Q3J3 InterPro	558