Gene
spag1a
- ID
- ZDB-GENE-030131-9443
- Name
- sperm associated antigen 1a
- Symbol
- spag1a Nomenclature History
- Previous Names
-
- spag1
- cb1089 (1)
- wu:fj78g10
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Involved in axonemal dynein complex assembly. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 28. Is expressed in several structures, including EVL; nervous system; pectoral fin musculature; periderm; and ventral mesenchyme. Orthologous to human SPAG1 (sperm associated antigen 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1089 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Knowles et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 28 | Alliance | Ciliary dyskinesia, primary, 28 | 615505 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ciliary Assembly and Mitochondrial Import | Tetratricopeptide-like helical domain superfamily | Tetratricopeptide repeat |
|---|---|---|---|---|
|
UniProtKB:F1RBN2
|
427 | |||
|
UniProtKB:A0A0H2UKG1
|
386 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spag1a-201
(1)
|
Ensembl | 2,050 nt | ||
| mRNA |
spag1a-202
(1)
|
Ensembl | 2,843 nt |
Interactions and Pathways
No data available
Plasmids
No data available