Gene
snx3
- ID
- ZDB-GENE-030131-921
- Name
- sorting nexin 3
- Symbol
- snx3 Nomenclature History
- Previous Names
-
- wu:fb53a08
- zgc:123189
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable phosphatidylinositol-3-phosphate binding activity. Involved in heme biosynthetic process. Acts upstream of or within erythrocyte differentiation and hemoglobin biosynthetic process. Predicted to be located in endosome and phagocytic vesicle. Predicted to be part of retromer complex. Predicted to be active in early endosome membrane. Is expressed in digestive system; hematopoietic system; and vascular endothelium. Human ortholog(s) of this gene implicated in syndromic microphthalmia 8. Orthologous to human SNX3 (sorting nexin 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Chen et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Phox homology | PX domain superfamily | Sorting Nexin | Vertebrate SNX3, PX domain |
|---|---|---|---|---|---|
|
UniProtKB:Q3B7E7
|
162 |
Interactions and Pathways
No data available
Plasmids
No data available