Gene

prss23

ID
ZDB-GENE-030131-9149
Name
serine protease 23
Symbol
prss23 Nomenclature History
Previous Names
  • fb01h12
  • wu:fb01h12
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have serine-type endopeptidase activity. Involved in atrioventricular valve development; endocardium morphogenesis; and regulation of Notch signaling pathway. Is expressed in atrioventricular canal; atrium; cardiac ventricle; and pectoral fin. Orthologous to human PRSS23 (serine protease 23).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Chen et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Chen et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prss23 Human Ortholog
No data available
Associated With prss23 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Domain IPR001254 Serine proteases, trypsin domain
Family IPR008256 Peptidase S1B
Family IPR050966 Glutamyl Endopeptidase
Homologous_superfamily IPR009003 Peptidase S1, PA clan
Homologous_superfamily IPR043504 Peptidase S1, PA clan, chymotrypsin-like fold
Domain Details Per Protein
Protein Length Glutamyl Endopeptidase Peptidase S1B Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site
UniProtKB:A0A8M1PSA1 373
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA prss23-201 (1) Ensembl 1,125 nt
mRNA prss23-202 (1) Ensembl 2,886 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations