Gene

cox8a

ID
ZDB-GENE-030131-9136
Name
cytochrome c oxidase subunit 8A
Symbol
cox8a Nomenclature History
Previous Names
  • coxXVIII (1)
  • fb01d11
  • hm:zehn2228
  • wu:fb01d11
  • zehn2228
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in oxidative phosphorylation. Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Is expressed in brain; gill; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to several human genes including COX8A (cytochrome c oxidase subunit 8A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Little et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cox8a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Mitochondrial complex IV deficiency, nuclear type 15 619059
Associated With cox8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR003205 Cytochrome c oxidase, subunit 8
Homologous_superfamily IPR036548 Cytochrome c oxidase, subunit 8 superfamily
Domain Details Per Protein
Protein Length Cytochrome c oxidase, subunit 8 Cytochrome c oxidase, subunit 8 superfamily
UniProtKB:E9QFA6 76
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations