Gene
tbxas1
- ID
- ZDB-GENE-030131-8805
- Name
- thromboxane A synthase 1 (platelet)
- Symbol
- tbxas1 Nomenclature History
- Previous Names
-
- wu:fk19d08
- zgc:136708
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to enable thromboxane-A synthase activity. Predicted to be located in endoplasmic reticulum membrane. Is expressed in heart. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome and cerebral infarction. Orthologous to human TBXAS1 (thromboxane A synthase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Scherz et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ghosal hematodiaphyseal syndrome | Alliance | Ghosal hematodiaphyseal syndrome | 231095 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cytochrome P450 | Cytochrome P450 3A | Cytochrome P450, conserved site | Cytochrome P450, E-class, group I | Cytochrome P450 superfamily |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6TGT4 | InterPro | 546 | |||||
| UniProtKB:Q1LUX9 | InterPro | 546 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tbxas1-201
(1)
|
Ensembl | 2,272 nt |
Interactions and Pathways
No data available
Plasmids
No data available