Gene

l3mbtl2

ID

ZDB-GENE-030131-8713

Name

L3MBTL histone methyl-lysine binding protein 2

Symbol

l3mbtl2 Nomenclature History

Previous Names

im:7137244
wu:fb04e09
zgc:66491

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have DNA binding activity; methylated histone binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Orthologous to human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66491 (1 image)
IMAGE:7137244 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With l3mbtl2 Human Ortholog

No data available

Associated With l3mbtl2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR006612	THAP-type zinc finger
Domain	IPR012313	Zinc finger, FCS-type
Family	IPR050548	Polycomb group and chromatin remodeling factors
Homologous_superfamily	IPR038603	FCS-type zinc finger superfamily
Repeat	IPR004092	Mbt repeat
Repeat	IPR047356	Lethal(3)malignant brain tumor-like protein 2, first MBT repeat
Repeat	IPR047357	Lethal(3)malignant brain tumor-like protein 2, second MBT repeat

Domain Details Per Protein

Protein	Length	FCS-type zinc finger superfamily	Lethal(3)malignant brain tumor-like protein 2, first MBT repeat	Lethal(3)malignant brain tumor-like protein 2, second MBT repeat	Mbt repeat	Polycomb group and chromatin remodeling factors	THAP-type zinc finger	Zinc finger, FCS-type
UniProtKB:F1R4V8 InterPro	805
UniProtKB:A0A8M2B270 InterPro	718
UniProtKB:A0A8M2B285 InterPro	804
UniProtKB:Q6PFI2 InterPro	805

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	l3mbtl2-201 (1) Ensembl	Ensembl	3,164 nt	Select Tool
mRNA	l3mbtl2-202 (1) Ensembl	Ensembl	1,157 nt	Select Tool
mRNA	l3mbtl2-203 (1) Ensembl	Ensembl	959 nt	Select Tool
mRNA	l3mbtl2-204 (1) Ensembl	Ensembl	5,771 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations