Gene

rpl10

ID

ZDB-GENE-030131-8656

Name

ribosomal protein L10

Symbol

rpl10 Nomenclature History

Previous Names

fa93d03
wu:fa93d03
zgc:56154 (1)

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Exhibits translation regulator activity. Involved in brain development; embryonic brain development; and regulation of translation. Predicted to localize to cytosolic large ribosomal subunit. Is expressed in head and midbrain hindbrain boundary. Human ortholog(s) of this gene implicated in autistic disorder and syndromic X-linked mental retardation 35. Orthologous to several human genes including RPL10 (ribosomal protein L10).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56154 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Brooks et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rpl10 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
syndromic X-linked mental retardation 35	Alliance	Intellectual developmental disorder, X-linked syndromic 35	300998
		{Autism, susceptibility to, X-linked 5}	300847

Associated With rpl10 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018255	Large ribosomal subunit protein uL16, conserved site, eukaryotes/archaea
Domain	IPR016180	Large ribosomal subunit protein uL16 domain
Family	IPR001197	Large ribosomal subunit protein uL16, eukaryotes/archaea
Family	IPR047873	Large ribosomal subunit protein uL16
Homologous_superfamily	IPR036920	Large ribosomal subunit protein uL16 superfamily

Domain Details Per Protein

Protein	Length	Large ribosomal subunit protein uL16	Large ribosomal subunit protein uL16, conserved site, eukaryotes/archaea	Large ribosomal subunit protein uL16 domain	Large ribosomal subunit protein uL16, eukaryotes/archaea	Large ribosomal subunit protein uL16 superfamily
UniProtKB:Q7ZV96 InterPro PDB	215

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rpl10-201 (1) Ensembl	Havana	760 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rpl10-202 (1) Ensembl	Havana	787 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rpl10-205 (1) Ensembl	Havana	848 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	rpl10-206 (1) Ensembl	Havana	828 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	rpl10-004 (1) Ensembl	Havana	763 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	rpl10-005 (1) Ensembl	Havana	805 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	rpl10-006 (1) Ensembl	Havana	887 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	rpl10-008 (1) Ensembl	Havana	728 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations