Gene

txndc9

ID

ZDB-GENE-030131-8569

Name

thioredoxin domain containing 9

Symbol

txndc9 Nomenclature History

Previous Names

fb15e07
wu:fb15e07
zgc:55522 (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to be involved in microtubule cytoskeleton organization. Predicted to be active in cytoplasm. Orthologous to human TXNDC9 (thioredoxin domain containing 9).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55522 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Allele	Type	Localization	Consequence	Mutagen	Supplier
sa13931	Allele with one point mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa17131	Allele with one point mutation	Unknown	Splice Site	ENU	Zebrafish International Resource Center (ZIRC) (order this) European Zebrafish Resource Center (EZRC) (order this)

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Sequence Targeting Reagents

No data available

Human Disease

Associated With txndc9 Human Ortholog

No data available

Associated With txndc9 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR013766	Thioredoxin domain
Homologous_superfamily	IPR036249	Thioredoxin-like superfamily

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Domain Details Per Protein

Protein	Additional Resources	Length	Thioredoxin domain	Thioredoxin-like superfamily
UniProtKB:Q7ZVX9	InterPro	226

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 9

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	txndc9-201 (1) Ensembl	Ensembl	1,313 nt	Select Tool ZFIN BLAST
mRNA	txndc9-202 (1) Ensembl	Ensembl	1,370 nt	Select Tool ZFIN BLAST
mRNA	txndc9-203 (1) Ensembl	Ensembl	735 nt	Select Tool ZFIN BLAST
mRNA	txndc9-204 (1) Ensembl	Ensembl	817 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-57A22	CR536604	ZFIN Curated Data
Encodes	EST	fb15e07	AI396824 AI397137
Encodes	cDNA	MGC:55522	BC045369	ZFIN Curated Data
Encodes	cDNA	MGC:85744	BC067598	ZFIN Curated Data
Encodes	cDNA	MGC:192512	BC165424	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_200021 (1)	1316 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR536604 (1)	217381 nt	Select Tool MegaBLAST
Polypeptide	UniProtKB:Q7ZVX9 (1)	226 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	TXNDC9	2	Ensembl:ENSG00000115514 Gene:10190 HGNC:24110 OMIM:612564	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)
Mouse	Txndc9	1	Ensembl:ENSMUSG00000058407 Gene:98258 MGI:2138153	Conserved genome location (synteny) (1) Amino acid sequence comparison (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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