Gene

cyfip1

ID
ZDB-GENE-030131-8557
Name
cytoplasmic FMR1 interacting protein 1
Symbol
cyfip1 Nomenclature History
Previous Names
  • CY (1)
  • CYFIP (1)
  • fb15a06
  • wu:fb15a06 (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have RNA 7-methylguanosine cap binding activity and actin filament binding activity. Involved in axon extension. Predicted to localize to SCAR complex; neuron projection; and synapse. Human ortholog(s) of this gene implicated in autism spectrum disorder and schizophrenia. Orthologous to human CYFIP1 (cytoplasmic FMR1 interacting protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Cioni et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyfip1 Human Ortholog
No data available
Associated With cyfip1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR009828 CYRIA/CYRIB , Rac1 binding domain
Family IPR008081 Cytoplasmic FMR1-interacting
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations