Gene

hadhb

ID
ZDB-GENE-030131-8550
Name
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
Symbol
hadhb Nomenclature History
Previous Names
  • fb14g10
  • wu:fb14g10
  • zgc:56274 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have acetyl-CoA C-acyltransferase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to localize to mitochondrion. Is expressed in female organism. Human ortholog(s) of this gene implicated in mitochondrial metabolism disease and mitochondrial trifunctional protein deficiency. Orthologous to human HADHB (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hadhb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mitochondrial trifunctional protein deficiency Alliance Trifunctional protein deficiency 609015
Associated With hadhb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR020610 Thiolase, active site
Active_site IPR020615 Thiolase, acyl-enzyme intermediate active site
Conserved_site IPR020613 Thiolase, conserved site
Domain IPR020616 Thiolase, N-terminal
Domain IPR020617 Thiolase, C-terminal
Family IPR002155 Thiolase
Homologous_superfamily IPR016039 Thiolase-like
Domain Details Per Protein
Protein Length Thiolase Thiolase, active site Thiolase, acyl-enzyme intermediate active site Thiolase, conserved site Thiolase, C-terminal Thiolase-like Thiolase, N-terminal
UniProtKB:Q7ZTH6 471
UniProtKB:A0A2R8RRC9 456
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations