Gene
hmgb1b
- ID
- ZDB-GENE-030131-8480
- Name
- high mobility group box 1b
- Symbol
- hmgb1b Nomenclature History
- Previous Names
-
- si:dkey-1m11.1
- wu:fa96c07
- wu:fb13a05
- zgc:165618
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity, bending and transcription factor binding activity. Predicted to be involved in several processes, including positive regulation of cellular metabolic process; positive regulation of cytokine production; and regulation of signal transduction. Predicted to localize to cytoplasm and nuclear chromatin. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is expressed in several structures, including axis; digestive system; intermediate cell mass of mesoderm; nervous system; and pleuroperitoneal region. Orthologous to human HMGB1 (high mobility group box 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | High mobility group box domain | High mobility group box domain superfamily | High Mobility Group Box (HMGB) | HMG box A DNA-binding domain, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:X1WFI9
|
197 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hmgb1b-201
(1)
|
Ensembl | 605 nt | ||
| mRNA |
hmgb1b-202
(1)
|
Ensembl | 1,187 nt | ||
| mRNA |
hmgb1b-203
(1)
|
Ensembl | 768 nt | ||
| mRNA |
hmgb1b-205
(1)
|
Ensembl | 841 nt | ||
| ncRNA |
hmgb1b-003
(1)
|
Ensembl | 291 nt |
Interactions and Pathways
No data available
Plasmids
No data available