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ZIRC
ZFIN ID: ZDB-GENE-030131-8410
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Gene Name: trafficking from ER to golgi regulator
Gene Symbol: tfg    Nomenclature History

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Previous Names: wu:fb11c10, zgc:55342, zgc:77230

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have identical protein binding activity. Predicted to be involved in COPII vesicle coating. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 57. Orthologous to human TFG (trafficking from ER to golgi regulator).
Genome Resources: Alliance (1),  Gene:336466 (1),  Ensembl(GRCz11):ENSDARG00000003641 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55342]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31722 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tfg HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Charcot-Marie-Tooth disease type 2 Alliance Hereditary motor and sensory neuropathy, Okinawa type 604484
    hereditary spastic paraplegia 57 Alliance ?Spastic paraplegia 57, autosomal recessive 615658
    DISEASE ASSOCIATED WITH tfg VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process COPII vesicle coating (more)
    Molecular Function identical protein binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000270 (1)
  • InterPro:IPR033512 (1)
  • InterPro:IPR034857 (1)
  • PROSITE:PS51745 (1)
  • Pfam:PF00564 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tfg-201 (1)    Ensembl 1872
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tfg No data available
    MARKER RELATIONSHIPS
    tfg Contained in: [BAC] CH211-283E2 (1) (order this)
    tfg Encodes: [EST] fb11c10
    [cDNA] MGC:55342 (1) (order this), MGC:77230 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200015 (1) 1809 bp
    Select Tool
    Genomic GenBank:BX322575 (1) 149874 bp
    Select Tool
    Polypeptide UniProtKB:Q6P0G5 (1) 396 aa
    Select Tool
    Sequence Clusters UniGene:10121 (1)
    Sequence Information (all 17)
    ORTHOLOGY for tfg ( Chr: 9 )
    CITATIONS (18)