Gene

tfg

ID
ZDB-GENE-030131-8410
Name
trafficking from ER to golgi regulator
Symbol
tfg Nomenclature History
Previous Names
  • wu:fb11c10
  • zgc:55342
  • zgc:77230
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have identical protein binding activity. Predicted to be involved in COPII vesicle coating. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 57. Orthologous to human TFG (trafficking from ER to golgi regulator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Chen et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa31722Allele with one point mutationUnknownPremature StopENU
1 - 1 of 1
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-tfgN/AChen et al., 2022
MO2-tfgN/AChen et al., 2022
1 - 2 of 2
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Human Disease
Associated With tfg Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease type 2 Alliance Hereditary motor and sensory neuropathy, Okinawa type 604484
hereditary spastic paraplegia 57 Alliance ?Spastic paraplegia 57, autosomal recessive 615658
1 - 2 of 2
Associated With tfg Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000270 PB1 domain
Domain IPR034857 TFG, PB1 domain
Domain IPR053793 PB1-like domain
Family IPR033512 Protein TFG
1 - 4 of 4
Domain Details Per Protein
Protein Length PB1 domain PB1-like domain Protein TFG TFG, PB1 domain
UniProtKB:Q6P0G5 396
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 9
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA tfg-201 (1) Ensembl 1,872 nt
mRNA tfg-202 (1) Ensembl 1,867 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-283E2ZFIN Curated Data
EncodesESTfb11c10
EncodescDNAMGC:55342ZFIN Curated Data
EncodescDNAMGC:77230ZFIN Curated Data
1 - 4 of 4
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanTFG3
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseTfg16
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
1 - 3 of 3
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