header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-8295
Gene Name: proteoglycan 4a
Gene Symbol: prg4a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: fb08a02, wu:fb08a02, wu:fk21a06, zgc:56698

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have polysaccharide binding activity and scavenger receptor activity. Predicted to be involved in immune response. Human ortholog(s) of this gene implicated in camptodactyly-arthropathy-coxa vara-pericarditis syndrome and pericarditis. Is expressed in caudal fin. Orthologous to human PRG4 (proteoglycan 4).
Genome Resources: Alliance (1),  Gene:336351 (1),  Ensembl(GRCz11):ENSDARG00000010482 (2)
GENE EXPRESSION
All Expression Data: Fig. 4 from Nolte et al., 2015
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
el687 Small Deletion Unknown Exon Loss TALEN
sa32889 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    TALEN1-prg4a 1
    TALEN2-prg4a 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prg4a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    camptodactyly-arthropathy-coxa vara-pericarditis syndrome Alliance Camptodactyly-arthropathy-coxa vara-pericarditis syndrome 208250
    DISEASE ASSOCIATED WITH prg4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process immune response (more)
    Cellular Component cellular_component (more)
    Molecular Function polysaccharide binding (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prg4a-201 (1)    Ensembl 1956
    prg4a-202 (1)    Ensembl 467
    prg4a-203 (1)    Ensembl 894
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prg4a No data available
    MARKER RELATIONSHIPS
    prg4a Contained in: [Fosmid] CH1073-202I11 (1) (order this)
    prg4a Encodes: [EST] fb08a02, fk21a06 (1)
    [cDNA] MGC:56698 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212753 (1) 2000 bp
    Genomic GenBank:CU638698 (1) 33978 bp
    Select Tool
    Polypeptide UniProtKB:B8JMI5 (1) 486 aa
    Sequence Clusters UniGene:76209 (1)
    Sequence Information (all 17)
    ORTHOLOGY for prg4a ( Chr: 2 )
    CITATIONS (17)